Can You Use Vitamin C and Peptide Serum Together?

Skincare Routines
Can You Use Vitamin C and Peptide Serum Together?

✨ Skincare Guides  ·  6 min read  ·  Last reviewed: September 2026

How to combine two popular skincare ingredients without making your routine unnecessarily complicated.

Vitamin C and peptides are often recommended for skin that looks dull, tired or less firm—but can they be used together?

Yes. For most people, vitamin C and peptide serums can form part of the same skincare routine.

You can either layer them during one routine or keep things simple by using vitamin C in the morning and peptides at night. The best approach depends on the formulations you are using, the sensitivity of your skin and how many other active ingredients are already in your routine.

What Does Vitamin C Do in Skincare?

Vitamin C is an antioxidant used in skincare to help defend the skin against environmental stress and improve the appearance of dullness and uneven tone.

Depending on the form of vitamin C and the complete formulation, a vitamin C serum may help:

  • Brighten dull-looking skin
  • Promote a more even-looking complexion
  • Provide antioxidant support
  • Improve the appearance of existing pigmentation
  • Support a smoother, healthier-looking skin surface

Naturals Beauty Glow Getter Vitamin C Serum contains Sodium Ascorbyl Phosphate, commonly abbreviated to SAP.

SAP is a stable, water-soluble vitamin C derivative. It provides antioxidant and brightening support in a formulation that can be easier to incorporate into a daily routine than some highly acidic vitamin C products.

What Do Peptides Do in Skincare?

Peptides are short chains of amino acids. Amino acids are the building blocks used to form proteins, including proteins associated with the skin’s structure.

Different cosmetic peptides have different functions. Depending on the peptide and formulation, they may help support the appearance of:

  • Firmness
  • Elasticity
  • Smoothness
  • Fine lines
  • Resilience
  • Overall skin vitality

Peptides do not stop ageing or instantly rebuild the skin. They are supportive ingredients that work best when used consistently as part of a balanced routine.

Can Vitamin C and Peptides Be Used Together?

In most cases, yes.

There is no universal rule requiring vitamin C and peptide products to be kept apart. Both can contribute to a routine focused on supporting healthy-looking skin, but they do so in different ways.

Vitamin C primarily provides antioxidant and brightening support. Peptides are included to support the appearance of firmness, smoothness and resilience.

This makes them complementary rather than interchangeable.

However, the way your skin responds depends on the complete formulas—not only the headline ingredients. A strongly acidic vitamin C formula, for example, may feel more intensive than a serum containing a gentler vitamin C derivative.

If your skin is sensitive or you are introducing both products for the first time, use them at different times of day initially.

What Is the Simplest Way to Use Them?

Our preferred starting routine is:

Morning: Glow Getter Vitamin C Serum

Apply Glow Getter after cleansing. Follow with moisturiser if needed and always finish with a broad-spectrum sunscreen.

Vitamin C provides antioxidant support during the day, while sunscreen helps protect the skin against ultraviolet exposure.

Evening: Re-Gen Peptide Power Serum

Apply Re-Gen after cleansing and before your moisturiser or facial oil.

This gives the peptide serum its own place in your routine and avoids introducing too many layers at once.

Using Glow Getter in the morning and Re-Gen at night is not mandatory. It is simply an easy, practical way to enjoy both serums.

Can You Layer Vitamin C and Peptide Serum?

Yes, you can layer the two serums if your skin tolerates them comfortably.

Apply products from the lightest consistency to the heaviest. If their textures are similar, you can apply the serum addressing your main skincare concern first.

A simple layered routine could be:

  1. Cleanse.
  2. Apply Glow Getter Vitamin C Serum.
  3. Allow it to absorb.
  4. Apply Re-Gen Peptide Power Serum.
  5. Follow with moisturiser.
  6. Apply broad-spectrum sunscreen during the day.

You do not need to wait for a precise number of minutes between serums. Allowing the first layer to absorb before applying the next is usually sufficient.

If the products pill or roll on the skin, try using a smaller amount, allowing slightly more time between layers or moving one serum to your evening routine.

Which Serum Should Be Applied First?

There is no single rule based solely on the words “vitamin C” and “peptides”. Texture is usually the most practical guide.

Apply the thinner, more fluid serum first and follow with the slightly richer formula.

If both serums have a similar consistency, apply the product connected to your main concern first. The more important factor is using a comfortable amount and giving each layer time to settle.

Is It Better to Use Vitamin C in the Morning?

Vitamin C is often used in the morning because its antioxidant activity complements daily sun protection.

It can help support skin exposed to environmental stress, but it does not replace sunscreen.

Your final daytime step should still be a suitable broad-spectrum sunscreen, applied generously and reapplied when necessary.

Vitamin C can also be used at night if that suits your routine better. Consistent use matters more than following a rigid rule.

Is Peptide Serum Better at Night?

Peptide serum can be used either in the morning or at night.

Many people prefer using peptides in the evening because it creates a simple division between active products:

  • Vitamin C in the morning
  • Peptides in the evening

However, Re-Gen Peptide Power Serum is suitable for AM and PM use. If you use it in the morning, apply sunscreen as the final step.

What Makes Re-Gen Peptide Power Serum Different?

Naturals Beauty Re-Gen Peptide Power Serum is a lightweight, fragrance-free serum formulated with two distinct peptide technologies and antioxidant-rich Malachite Extract.

Reneseed™ technology at 2%

Reneseed™ is a plant-produced biomimetic peptide technology used to support smoother, firmer-looking skin and the appearance of skin vitality.

The 2% refers to the Reneseed™ technology used in the formulation. It should not be described as 2% pure peptide or combined with the percentage of another peptide ingredient.

Copper Tripeptide-1 at 0.005%

Copper Tripeptide-1 is a cosmetic peptide used in formulations designed to support the appearance of skin renewal, resilience and firmness.

Malachite Extract

Malachite Extract provides antioxidant support, helping the formula care for skin exposed to environmental stress.

Glycerin and Pentylene Glycol

These humectants help attract and retain moisture, supporting a hydrated and comfortable skin feel.

Can Copper Peptides Be Used With Vitamin C?

Copper peptides and vitamin C are often said to be completely incompatible, but this is an oversimplification.

Whether products work comfortably together depends on their complete formulations, including the form of vitamin C, product pH and the sensitivity of the person using them.

Glow Getter uses Sodium Ascorbyl Phosphate, a stable vitamin C derivative, while Re-Gen contains Copper Tripeptide-1 at 0.005%.

If you would prefer the most straightforward routine, use Glow Getter in the morning and Re-Gen in the evening. This allows you to include both products without needing to layer them.

If you choose to use them together, introduce the combination gradually and observe how your skin responds.

Should Sensitive Skin Use Both Serums at Once?

Sensitive skin may benefit from a slower introduction.

Begin with one serum and use it consistently for several days before adding the second. This helps you determine how your skin responds to each formula individually.

You could begin with:

  • Glow Getter on two or three mornings per week
  • Re-Gen on alternate evenings
  • Moisturiser as needed
  • Sunscreen every morning

Increase the frequency gradually if your skin remains comfortable.

If you experience persistent burning, redness, itching or irritation, stop using the new product and reassess your routine.

What If You Also Use Retinol or Exfoliating Acids?

A routine containing vitamin C, peptides, retinoids and exfoliating acids can quickly become more complicated than necessary.

You do not need to use every active ingredient every day.

One possible schedule is:

Morning

  • Gentle cleanser
  • Glow Getter Vitamin C Serum
  • Moisturiser
  • Broad-spectrum sunscreen

Evening routine one

  • Gentle cleanser
  • Re-Gen Peptide Power Serum
  • Moisturiser or facial oil

Evening routine two

  • Gentle cleanser
  • Retinoid or exfoliating product
  • Moisturiser

Alternate the evening routines according to your skin’s needs and tolerance.

This is only a general example. If you use prescription skincare or are managing a skin condition, follow the advice of your qualified healthcare professional.

Which Product Should You Choose if You Only Want One?

Choose according to your main concern.

Glow Getter Vitamin C Serum may be the better starting point if your priority is:

  • Dullness
  • Uneven-looking tone
  • The appearance of pigmentation
  • Daytime antioxidant support

Re-Gen Peptide Power Serum may be the better starting point if your priority is:

  • Fine lines
  • Reduced firmness
  • Loss of elasticity
  • Skin that feels less resilient
  • Gentle age-support care

If both groups of concerns are relevant, the serums can be used in the same overall routine.